C7 anticorps (C-Term)
Aperçu rapide pour C7 anticorps (C-Term) (ABIN206670)
Antigène
Voir toutes C7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- Recognizes complement component 7 (C7), a 110 kD glycoprotein present in the blood serum. The factor I domain of C7 binds the C terminus of the C5 alpha-chain, acting as a membrane anchor. This enables the assembly of the complement membrane attack complex (MAC) and consequent complement lytic activity. C7 deficiency is associated with increased susceptibility to recurrent infections, in particular by Neisseria meningitides. Note that Does not recognize membrane bound complement membrane attack complex. Inhibits lysis of sensitized sheep erythrocytes.
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Purification
- Protein A purified
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Immunogène
- Purified human C7.
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Isotype
- IgG1
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Indications d'application
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Approved: ELISA, Func, WB
Not recommended for: IHC-P -
Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- BBS, 0.1 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- C7 (Complement Component C7 (C7))
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Autre désignation
- Complement C7
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Sujet
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Name/Gene ID: C7
Subfamily: Complement Component
Synonyms: C7, Complement C7, Complement component 7, Complement component C7 -
ID gène
- 730
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UniProt
- P10643
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Pathways
- Système du Complément
Antigène
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